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39,40 In addition to engaging classical Fc receptors on the cell membrane, antibodies exert potent immune functions from inside cells via a unique cytosolic receptor for IgG Fc, which is called TRIM21

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This is used for a number of vital functions as an important enzyme in the Krebs cycle, for synthesis of heme, cytochrome P450 enzymes and nucleotides

doi: 10.3390/ijms23010183

The combination of the PS structural motif with stable radical may lead to stimulation of higher ROS production
