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First, -glutamylcysteine is synthesized from cysteine and glutamate catalyzed by gamma-glutamylcysteine synthetase

Reis CG, Mocelin R, Benvenutti R, Marcon M, Sachett A, Herrmann AP, et al

however, crizotinib can restore panitumumab and MM-151 sensitivity in SC and CC-CR (Graves-Deal et al., 2019)

10.1161/01.CIR.102.23.2867 148

Other reagents for peptide synthesis and cleavage, including GSH, dichloromethane (DCM), N, N-dimethylformamide (DMF), acetonitrile, Tris-(2-carboxyethyl) phosphine (TCEP), triisopropylsilane (TIPS), N, N-diisopropylethylamine (DIEA), p-cresol and guanidine hydrochloride (GuHCl) were purchased from Sigma-Aldrich

(2020) 180:1098114.e16