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The effects of the KD on patients with familial hypercholesterolaemia is uncertain, although some data suggest possible exacerbation of hypercholesterolaemia and uncertain safety levels in these cases [163]
Analogs targeting arginase and arginine deiminase, the enzymes involved in arginine depletion, have been developed
CrossRef Role of ATP-binding cassette transporter A1 in suppressing lipid accumulation by glucagon-like peptide-1 agonist in hepatocytes Jingya Lyu, Hitomi Imachi, Kensaku Fukunaga, Seisuke Sato, Toshihiro Kobayashi, Tao Dong, Takanobu Saheki, Mari Matsumoto, Hisakazu Iwama, Huanxiang Zhang, Koji Murao Molecular Metabolism.2020
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