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Finally, future studies should include robust secondary endpoints that assess cognitive function, quality of life, and functional recovery, not just symptom reduction [199]

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Temporary relief becomes common when one or more of these issues remains unaddressed: Blood flow remains limited , which slows repair Inflammation remains reactive , which disrupts collagen rebuilding Collagen remodeling remains incomplete , which leaves the tissue weak Stability remains impaired , which keeps load distribution dysfunctional This is where peptide protocols can be useful