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This could be due to a variety of reasons such as genetic factors, underlying health conditions like pernicious anaemia, or gastrointestinal surgery

Inflammation Chronic inflammation disrupts normal nerve signaling and can lead to neurological imbalances that can potentially contribute to RLS symptoms

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10.1016/S0300-2977(00)00048-6

Our group, working with partially deficient IGF-1 mice, has demonstrated that the liver is capable of expressing IGF-1R (which under physiological conditions it does not [99]) as a defence mechanism (peer review)

So, with little previous research in this area we were keen to understand why this was the case and to find out what impact there was on the safety of patients. She added: We believe there is an opportunity for healthcare professionals to encourage patients to come to them for advice as our research showed that 72% are finding information around medication from online, closed support groups