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It is produced primarily in the liver and kidneys and stored in muscle tissue, where it supports energy metabolism

Injection site reactions such as redness, itching, or mild swellingoccur in approximately 2-3% of patients and are generally self-limiting

Laboratory evaluation usually reveals hypoglycemia with minimal or no ketones in urine and hyperammonemia with variably elevated liver function tests

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5) While some associations have been observed, particularly with gout and renal diseases, evidence from Mendelian randomization studies did not consistently support a causal relationship between elevated serum urate levels and other metabolic or cardiovascular disorders

CD8 + T cell metabolism in infection and cancer