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Results Erucamide is downregulated during retinal degeneration Using high-resolution global mass spectrometry-based metabolomics, we cataloged the metabolites dysregulated during retinal degeneration in an animal model of RPE-mediated retinal degeneration, the Royal College of Surgeons (RCS) rat

21 Impaired detoxification of reactive metabolites via a deficiency in glutathione, cysteine, and ascorbate, may play a role, and theoretically supports the use of glutathione precursors (NAC, SAMe) and vitamin C in treatment

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