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Additionally, it was reported that trimetazidine (TMZ), a piperazine derivative, mediated activation of the GSH system and had antioxidant and cytoprotective effects in several myocardial injury models [210,211,212,213]

Zhang L-J, Liu M-Y, Rastogi R, Ding JN

100 TakahashiS.MashimaK

Nature (2015) 526:6605

In contrast, the PRP/PC group demonstrated heterogeneous histological findings, where some seminiferous tubules showed nearly complete spermatogenesis, while others contained necrotic cells within constricted lumina, indicating variable and uneven regenerative responses