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Although these substances are more effective in cases where cognitive functions are obviously impaired, they are of interest to healthy individuals because of their ability to increase intelligence and improve memory [2]

Snapshot Proponents Effective for L-carnitine deficiency Supports mitochondrial health and energy function Allegedly supports liver and brain health May improve PCOS in women and semen quality and fertility in men Skeptics Many popular uses are not supported by evidence May contribute to heart disease by metabolizing TMAO Can cause nausea or stomach upset Long-term use may cause oxidative stress in the liver and blood Affects thyroid function Health Benefits of Carnitine Effective for: L-Carnitine Deficiency (Genetic) Oral and intravenous L-carnitine is effective for the treatment of primary and secondary L-carnitine deficiency due to inborn errors of metabolism (genetic)

Drugs under Experimental and Clinical Research 12: 925935, 1983 Pongratz D, Hbner G, Deufel T, Wieland O, Pongratz E, et al

Improved Exercise Performance: Athletes and fitness enthusiasts often turn to L-Carnitine to enhance their endurance and overall exercise performance

Levels of both enzymatic and nonenzymatic antioxidants are inhibited and the levels of oxidants increase in the liver, kidney and gut tissues of laboratory animals given methotrexate [10, 14]

Meng et al