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Antioxidant and pro-oxidant effects of polyphenolic compounds and structure-activity relationship evidence

But there are several obstacles to the development of this senolytic approach such as the long-term effect of CAR-T cells therapy with possible aspecific toxicity in different organs 56 , the cost and the difficulty during process development 57 or the selection of non-exhausted T cells to generate efficient therapy 58,59

This flexibility in dosing options allows healthcare providers to customize treatment regimens based on individual patient responses, tolerability, and therapeutic goals

MiR-135b-5p is an oncogene in pancreatic cancer to regulate GPRC5A expression by targeting transcription factor KLF4