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All children showed mitochondrial enzymatic abnormalities on the MitoSwab assay at baseline

doi: 10.17179/excli2022-5617 2 AnandS.MandeS

A single, intravenous or intranasal sub-anesthetic dose of ketamine, a non-competitive NMDA glutamate receptor channel blocker, produces a rapid onset of antidepressant response that can last several days in the majority of treatment resistant unipolar and bipolar depressed patients participating in a growing number of clinical trials 148150

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