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McCourt, M., Wang, J

Screening and diagnosing strategy for vitamin B12 deficiency in patients with type 2 diabetes on metformin therapy

The peptide net charge alone could not fully estimate mucosa transport efficiency

The treatment group demonstrated significant improvements in one-hour time-trial performance on a running track, along with favorable shifts at the aerobic and anaerobic thresholds.8 These were moderately trained runners showing measurable endurance gains that exceeded what concurrent training alone produced

This suggests that while there may be patient circumstances where methylene blue is beneficial, researchers have not yet pinned down what those are

The missing pieces are big: no human dosing, no human pharmacokinetics, no controlled human safety data, and no long-term outcome data in any species