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Bioorg Chem 60:4957 [DOI] [PubMed] [Google Scholar] Oztaskin N, Taslimi P, Mara A, Gksu S, Gulcin I (2017) Novel antioxidant bromophenols with acetylcholinesterase, butyrylcholinesterase and carbonic anhydrase inhibitory actions

DHT: GHK-Cu acts as a mild localised 5-alpha reductase inhibitor

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In cases where CR was achieved, treatment was stopped after 6 months

Hepatitis B viral HBx induces matrix metalloproteinase-9 gene expression through activation of ERK and PI-3K/AKT pathways: Involvement of invasive potential

Given their broad CYP liabilities and limited binding improvement, the oxime modification appears less attractive for this series
