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The potential risks posed by the injectable skin whitening products include nerve or blood vessel damage, infection, and toxic systemic reactions

Furthermore, it has been shown that endothelin-1 and VEGF, which are responsible for enhanced vascularity in melasma lesions, can be diminished by tranexamic acid administration

doi: 10.1038/347151a0

Patients with HT who received replacement with levothyroxine (L-T4) did not always achieve clinically significant results, which requires additional therapeutic agents ( The significant prevalence of AITD, a long latent period and the involvement of autoimmune processes in their occurrence, development of concomitant diseases, insufficient effectiveness of the main pharmacotherapy, and a decrease in the quality of life of patients require the development of adequate approaches for the correction of immune processes in order to prevent and treat diseases