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While oral alternatives are being developed, injectable medications currently lead the market in terms of efficacy and patient outcomes

OLeary, J

Carbamidomethylation of cysteine (+57 Da) was considered a fixed modification, while variable modifications included oxidation of methionine to methionine sulfoxide (+16 Da), deamidation of Asn to Asp (+1 Da), conversion of Asp to isoAsp, followed by the incorporation of a deuteron (+1 Da), and conversion of Asn to isoAsp, followed by the incorporation of a deuteron (+2 Da)

Glucagon receptor agonism increases energy expenditure and promotes hepatic fatty acid oxidation, which may contribute to reductions in liver fat content