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This combination of enzymatic degradation and decreased cellular production leads to a gradual loss of skin density and firmness, promoting premature skin aging

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However, this does not mean that EVs are perfect delivery carriers, as challenges such as large-scale production, standardization of separation techniques, and batch-to-batch reproducibility remain key obstacles for clinical translation (Wang et al., 2021)

Bacteriostatic water, sterile and anti-bacterial, in gas-tight sterilised clear vials, sealed with a pre-sterilised rubber septum by gamma-irradiation and a centre tear-out crimp seal