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194 Currently, apelin is being considered as a biomarker and drug target, but its role in the development of both obesity and type 2 diabetes needs to be clarified with convincing clinical studies

Biochem Biophys Res Commun 231:488493 [DOI] [PubMed] [Google Scholar] 68.Ladds E, Rushforth A, Wieringa S, Taylor S, Rayner C, Husain L, Greenhalgh T (2020) Persistent symptoms after Covid-19: qualitative study of 114 long covid patients and draft quality principles for services

For example in patients with obesity, L-carnitine directly reduces all free fatty acids in the plasma by transporting them to the mitochondria [83]

Another study also aimed to compare the effectiveness of resveratrol supplementation versus aerobic exercise training, both combined with a low-fat diet, on adipogenesis and inflammation-related markers in adipose tissue of high-fat diet-induced obese mice (101)