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2-vessel (2-VD), n=66

This study provides the basis for future screening studies to verify if animals have been exposed to toxicologic insults

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Compound CID 950107. National Center for Biotechnology Information

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Moreover, inflammatory mediators, such as Nucleotide-binding oligomerization domain-like receptor protein 3 (NLRP3) and Tumor necrosis factor-alpha (TNF-) increased, while pivotal proteins involved in dendritic and synaptic development, such as Synaptophysin (SYP), postsynaptic density protein 95 (PSD95) and brain-derived neurotrophic factor (BDNF) decreased in APP/PS1 mice