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Traditional Chinese medicine Lingguizhugan decoction ameliorate HFD-induced hepatic-lipid deposition in mice by inhibiting STING-mediated inflammation in macrophages

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Together, these shuttling systems effectively involve the first and last steps of the TCA cycle to run forward in the mitochondria and then reverse in the cytosol, with the net effect being the movement of electrons into the mitochondria (in the form of NADH) and carbon into the cytosol (in the form of Ac-CoA)

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