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Further studies are required to define whether ECs with subclonal loss of MMR protein expression have a similar TMB and are equally predictive of ICI response compared to those with complete MMR protein loss

Fabrication of dual pH/redox-responsive lipid-polymer hybrid nanoparticles for anticancer drug delivery and controlled release

Mechanistically, we find that GSH promotes lipid abundance by repressing NRF2, a transcription factor induced by oxidative stress

doi: 10.1111/j.1365-2265.2006.02494.x

If you could discuss your own evolution and how you view the aging issue

Tripartite-motif protein 21 knockdown extenuates LPS-triggered neurotoxicity by inhibiting microglial M1 polarization via suppressing NF-kappaB-mediated NLRP3 inflammasome activation