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[DOI] [PMC free article] [PubMed] [Google Scholar] 112.Ogger PP

Int J Neuropsychopharmacol 14(1):123130

Despite decades of investigation and an expanding array of molecular targets and candidate therapeutics, the field continues to struggle with the lack of a standardized and universally accepted definition of neuroprotection

GLO1 then converts the hemithioacetal into S-D-lactoylglutathione, which is later recognized by glyoxalase 2 (GLO2, EC 3.2.1.6) and hydrolyzed to d-lactate [19]

Glutathione, being a natural antioxidant, may present a gentler alternative, but results may take longer to manifest

Two-month treatment of obese subjects with the oral growth hormone (GH) secretagogue MK-677 increases GH secretion, fat-free mass, and energy expenditure