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However, damage to this barriersometimes referred to as intestinal permeability or leaky gutcan allow inflammatory compounds such as bacterial endotoxins to enter the bloodstream

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doi: 10.1016/S1097-2765(02)00519-1

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152 The normal production and turnover of ECM is a complex process that requires coordination of inputs from epithelial cells, endothelial cells, innate and adaptive immune cells, and nerves (Figure 4B)

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