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This intricate relationship suggests that ferroptosis might be a direct consequence of lipid peroxidation

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It is important to note that few studies have examined omics biomarkers in relationship to existing clinical criteria, such as coma or a constellation of clinical and laboratory findings (i.e., Kings College Criteria) currently in use by clinical practitioners as a prognostic indicator

It has been reported that lung cancer cells exhibit upregulated expression of all key glycolytic enzymes [hexokinase 2 (HK2), phosphofructokinase and pyruvate kinase (PK)] (13), suggesting that the essential enzymes of the aerobic glycolytic pathway have a critical role in the development of lung carcinoma

90 AGEs also increased ROS expression