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Microglia activation is usually followed by proliferation and release of pro-inflammatory cytokines such as TNF-, IL-1 and IL-6 [48], while there is strong evidence that this inflammatory state can lead to neuronal death in vitro and in vivo [49, 50]

Neurology 1991;41:1726-32

21 L-carnitine helps protect the stability of cell membranes, enhances human immune function, helps guard against certain diseases, and plays a certain preventive role in managing suboptimal health

Table 15 shows the studies in this review that investigated the remission effect of LC supplementation in patients with MS

C12) (Nimbkar et al., 2022)

Brain Function Some studies demonstrate a potential for reducing blood pressure and the inflammatory process associated with heart disease (x) (xx)