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Other AD-associated pathology, including neuroinflammation and oxidative stress, may also impair the development of oligodendrocytes and myelination [111, 115]

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Various studies have found a significant, independent association between GGT levels and both cardiovascular and all-cause mortality.2022 High GGT levels have been shown to be associated with a poorer prognosis in coronary artery disease and heart failure.23,24 A possible pathogenic implication of GGT in the formation of atherosclerotic plaque, its erosion and subsequent rupture has also been observed,25 which could help explain its relationship with cardiovascular morbidity and mortality from a biological point of view

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When the skin is pink, the hair follicle is in the dormant phase, and when the skin turns gray, the hair follicle is in the anagen phase [51,52]