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However, aminochrome can be neurotoxic when it forms adducts with proteins such as alpha-synuclein, alpha- and beta-tubulin, and H-type ATPase, or when aminochrome is one-electron reduced by flavoenzymes that use NADH, generating redox cycling, depletion of energy, and the formation of reactive oxygen species

El-Saadony MT, Saad AM, Korma SA, Salem HM, Abd El-Mageed TA, Alkafaas SS, Elsalahaty MI, Elkafas SS, Mosa WFA, Ahmed AE, Mathew BT, Albastaki NA, Alkuwaiti AA, El-Tarabily MK, AbuQamar SF, El-Tarabily KA, Ibrahim SA (2024) Garlic bioactive substances and their therapeutic applications for improving human health: a comprehensive review

These results demonstrated that in early stages of infection coronatine may play a critical role by suppressing activation of defense-related genes including GSTs (Mittal and Davis, 1995)

10.1001/archderm.142.2.206 204 SalehF.Abdel-AzimE.RagaieM.GuendyM

Vaccine 37 , 23402347 (2019)

Isotope-reinforced (deuterated) PUFA (D-PUFA) is effective in reducing lipid peroxidation and A level in the APP/PS1 transgenic mouse model of Alzheimers disease