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Other negative effects of metHb accumulation include its toxicity related to protein tyrosine nitration, protein oxidation, and lipid oxidation (53)

Acting primarily as an antioxidant, glutathione protects cells from oxidative stress caused by free radicals, which can lead to cellular damage and various health issues

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doi: 10.1038/ki.1992.224

High Oxidative Stress Exposure: Smokers and Heavy Alcohol Users: Who experience significantly increased oxidative burden

110 A originates from the processing of the APP, a transmembrane glycoprotein, through its sequential cleavage by -secretase and -secretase (a multiprotein complex with PS1 or PS2 as catalytic subunits)