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It may also support healthy aging by protecting cells from damage

Annu Rev Cell Dev Biol

Patients seeking moderate weight loss (10-15% body weight): Orforglipron's Phase 3 data show mean weight loss of approximately 11% at 72 weeks, with about 55% of participants achieving 10% or greater loss

The feces also show that a high amount (up to 98%) of the excreted B12 are cobalamin analogues, due to the conversion of cobalamin into analogues by microorganisms in the colon
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[DOI] [PubMed] [Google Scholar] 39.Boozer CN, Leibel RL, Love RJ, Cha MC, Aronne LJ