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[DOI] [PMC free article] [PubMed] [Google Scholar] 177.Reid G, Jass J, Sebulsky MT, McCormick JK

By comparing the samples from the I/R and I/R + M groups, it can be concluded that the prevalence and intensity of liver regeneration is significantly higher in the animals pre-treated with meldonium 68 , proved with the lower Suzuki histological score in samples from the I/R + M group in comparison to samples from the I/R group (Table 6)

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According to Bunney et al., PLC is localized in cytoplasm in self-inhibited mode, while binding of Ras stimulates it to change its conformation and to translocate to the membrane [8]