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To generalize our results, we searched for genic deletions that are polymorphic in both humans and chimpanzees

NAC treatment significantly increased the relative protein expression of collagen type 1 alpha 1 (COL1A1), tenascin C (TNC), scleraxis (SCX), and tenomodulin (TNMD) in TPSCs

Finally, the review addresses critical challenges for clinical translation, including tumor heterogeneity, safety concerns regarding off-target toxicity, and the urgent need for predictive biomarkers and advanced nanodelivery systems

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