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It is not best suited for severe osteoarthritis, advanced cartilage loss, major joint deformity, complete tendon rupture, fracture, or injuries requiring surgical evaluation
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NICE technology appraisal TA875 (2023) recommends semaglutide 2.4 mg (Wegovy) as an adjunct to a reduced-calorie diet and increased physical activity for adults with a BMI of 35 kg/m or above (or 3034.9 kg/m in certain circumstances) alongside at least one weight-related comorbidity, when initiated within specialist weight management services
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