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Moreover, the crystal structure of Gbs MerA and structural comparison with homologues indicated that Gbs MerA contains residues, Tyr437 and Asp47, which may be responsible for metal transfer at the si -face by providing a hydroxyl group (OH) to abstract a proton from the thiol group of cysteine

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doi: 10.1186/1741-7015-12-112, 113

Insulin resistance (IR) refers to the reduced sensitivity and reactivity of insulin target organs (liver, adipose tissue and skeletal muscle) to endogenous or exogenous insulin, resulting in lower glucose uptake and utilization than normal (Haas et al., 2016)

Energetic and nutritional constraints on infant brain development: implications for brain expansion during human evolution

doi: 10.1007/s10803-022-05784-9 107 PaganoG.LyakhovichA.PallardF