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Drug Discovery Today , 18(1718), 807817

All right, good
Megaloblastic anaemiacharacterised by abnormally large, immature red blood cellsdevelops when B12 deficiency impairs DNA synthesis
Eukaryotes lack this capacity and in particular complex animals can excrete absorbed Mercury only with difficulty, therefore most of the dose accumulates over time in long-half-life forms, from which the metal can be released and reach biochemically-impairing levels and thus exert toxic effects

The issue is that when we age, get injured, live under stress, or have inflammation, the bodys natural peptide signals get diminished
