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[DOI] [PMC free article] [PubMed] [Google Scholar] 114.Barakat A
MiR-27a inhibits the expression of several lipid metabolic genes, including SREBP1-2, FASN, and PPAR/, by reducing lipid synthesis and increasing lipid secretion from cells 92
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However, the typical symptoms in a CKD patient, such as tiredness, impaired cognition, muscle weakness, myalgia, and muscle wasting, were found significantly attenuated and improved the health of patients as well as the kidney [69]
doi: 10.1007/s12020-019-01882-4 19 PattisonDJHarrisonRASymmonsDP
This lack of homeostasis affects acidification of vesicles transported to the lysosomal compartment for degradation [114]
