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Microbial-host interplay in TMAO synthesis and metabolism TMAO originates from dietary precursors metabolized through a tightly coordinated interplay between gut microbiota and host hepatic enzymes (50)

One group received only the medications, another received the medications plus ALC, and the third group received placebo

The NCBI conducted a clinical trial, which fund that it may aid athlete recovery and help reduce muscle soreness

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Ross JM, berg J, Bren S, Coppotelli G, Terzioglu M, Pernold K, Goiny M, Sitnikov R, Kehr J, Trifunovic A, Larsson N-G, Hoffer BJ, Olson L (2010) High brain lactate is a hallmark of aging and caused by a shift in the lactate dehydrogenase A/B ratio

Neuroscience 165:13451352
