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Starting conservatively and adjusting based on individual response remains the best approach to minimize any negative effects while maximizing benefits

In conditional mouse mutants, in which the expression of the Igf1r gene was ablated exclusively in neurons and OPC of the cerebrum, there was a reduced accumulation of OPC, leading to a decreased amount of newly generated oligodendrocytes (Mason et al., 2003)

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Safety Monitoring and Personalized Response: Before You Start Regardless of Medicaid coverage status, GLP-1 therapy requires baseline screening for contraindications: personal or family history of medullary thyroid carcinoma, multiple endocrine neoplasia type 2, severe pancreatitis, and gastroparesis

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