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Extracell Vesicles 7 , 1535750 (2018)

10.1016/j.jtherbio.2019.102449 J Therm Biol

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In humans, hydroxyphenylpyruvate dioxygenase-like protein (HPLD) converts 4-HPP to 4-hydroxymandelate (4-HMA) [41]

Therefore, intravenous administration of glutathione, which is used in many diseases, is the best option to achieve the highest possible effect

Vedolizumab is a humanised monoclonal antibody that inhibits lymphocyte adhesion, particularly the mucosal addressin cell adhesion molecule-1 (MAdCAM-1), which is selective for 47 integrin[86]