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Studies in rats and mice show that melatonin has toxic effects if given at extremely high doses (more than 400 mg/kg), but this is tens of thousands of times more than the recommended dose for treating sleep disorders, which varies between 2-10 mg

Both treatments produced significant improvements in depression, overall well-being, and physical functioning

Additionally, because ALA acts as a potent chelator of heavy metals, it can also bind to essential dietary minerals if taken simultaneously

Date of manufacture and batch number marked on bottom of the package

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