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doi: 10.3390/antiox10091491 118 HermelM.SweeneyM.NiY.-M.BonakdarR.TriffonD.SuharC.et al

Overdosing is rare due to vitamin B12s safety profile, though always follow prescribed dosing to avoid complications
10.4142/jvs.2011.12.3.267 71

A standard starting dose in both men and women is 1mg daily

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Humanized mice with Gilbert syndrome gene promoter polymorphism (HuUGT1A1*28) [with knocked out from the mouse locus] were shown to have mildly elevated bilirubin levels and resistant to high-fat-diet-induced fatty liver disease and glucose intolerance [15]
