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Vitamin C has been shown to enhance levodopa bioavailability and kinetics of absorption in patients with PD (Nagayama et al

MGO is linked to microvascular dysfunction, and maintaining the integrity of the bloodbrain barrier (BBB) is essential for optimal brain function [267]

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Two more broad approaches are (i) the inactivation of the Trsp gene [80], which completely prevents the biosynthesis of all selenoprotein, (ii) while Scly inactivation [81] blocks the cellular recycling of Se/selenide contained in the Sec of selenoproteins

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