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Vossen, A., van Doorn, M

The knockout of ATM can also lead to an increase in H 2 O 2 within HSCs and induce excessive proliferation and differentiation of HSCs through the activation of the p38-MAPK pathway, ultimately leading to HSC exhaustion [294]

Nature 552 , 5156 (2017)

By identifying specific loxP sites, Cre facilitates the deletion of gene sequences located between these sites, enabling precise genetic modification at defined genomic loci

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Inherited disorders in the conversion of methionine to homocysteine
