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Roles of bile acids signaling in neuromodulation under physiological and pathological conditions

They propose that under the stimulation of the pro-inflammatory cytokine TNF- , IRF1 can directly bind to the GPX4 promoter region (1,498 to 1,239), affecting GPX4 transcription
The rats of all groups were supplied with a control diet prepared with 71% carbohydrate, 18% protein, 7% fat, and 4% salt mixture and water ad libitum 1

[DOI] [PubMed] [Google Scholar] 22.Beauchamp C., Fridovich I

During the aging process, the expression of NRF2dependent antioxidant enzymes decreases, thereby leading to oxidative stress and related diseases [176]
10.1007/s12041-010-0030-1
