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While transporters seem to have remained somewhat understudied (153) , those transporters involved in uptake and encoded by the human genome are now catalogued formally as SLC for solute carriers (154,155) , with efflux transporters mainly being classed as ABC families (156)

doi: 10.3390/molecules27082484 72

doi: 10.1038/s41582-023-00845-8 160 LumJ

C., Kilbane, E

For disorders in which the defective gene is known, a combination of mutation analysis and biosynthetic studies is used to understand the mechanisms by which the mutations arise, the inheritance pattern of each disorder, and the effect of each mutation of the synthesis, structure, and function of the encoded protein
