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Mechanistically, GSTZ1 depletion enhanced the activation of the Nrf2 pathway and increased the GPX4 level, thereby suppressing sorafenib-induced ferroptosis (Wang Q

Whether through externally applied stimuli (ultrasound, light, magnetic fields) or intrinsic catalytic reactions, these modalities are designed to concentrate cytotoxic agentssonosensitizers, photosensitizers, thermal converters, or Fenton catalystswithin the acidic, enzyme-rich lysosomal lumen

COXs oxidize arachidonic acid into prostaglandins, modulating inflammation and apoptosis (20)

Because NAD+ and peptides do different jobs, they are often complementary rather than redundant

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Furthermore, this study found that like other micronutrients umbilical cord blood from smoking mothers had reduced manganese concentrations [124]