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This stress is often amplified by drought and high temperatures (Kumar 2020) and manifests as osmotic imbalance, ionic toxicity, and excessive reactive oxygen species (ROS) production, which disrupt redox homeostasis, cell division, membrane integrity, and cytoplasmic metabolism (Mushtaq et al

The disease-associated r(GGGGCC)n repeat from the C9orf72 gene forms tract length-dependent uni- and multimolecular RNA G-quadruplex structures

The approach adds complexity but extends useful product life for users with lower consumption rates

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When blocking glucose metabolism, tumor cells rapidly adapt to metabolic inhibition by switching energy pathways (e.g., glutaminolysis or fatty acid oxidation), limiting the efficacy of glycolysis inhibitors like 2-DG or HK2-targeting agents [129]