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M.CochemeH

CrossRef Retrospective comparison of individual risk factors hemithyroidectomy and thyroidectomy in patients with papillary carcinoma of the thyroid gland in combination with autoimmune thyroiditis E

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6 The potential of ferroptosis in PD early diagnosis It is estimated that by the time motor deficits are detected and individuals with PD receive a clinical diagnosis, they may have lost 3050% of their dopaminergic neurons, accompanied by a 5060% reduction in striatal dopamine (212), underscoring the critical need for early diagnosis in PD treatment

Thus, physiological radical ROS flux operates within a tightly controlled spatial relay system (O 2 H 2 O 2 ), enabling localized redox cues to be transduced into adaptive signals for cell survival, metabolic plasticity and immune homeostasis, while loss of this control drives pathological, switch-like transitions toward cell death, metabolic dysfunction and pathological inflammation
