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To generate recombinant adenovirus packaging plasmids, shuttle vectors were linearized by Pme I and transformed into AdEasier competent cells

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Repeat-dose senolytic protocols should space administrations 1014 days apart to allow macrophage-mediated clearance of apoptotic debris before introducing subsequent doses

By contrast, the observation that Wnt signaling activity is elevated specifically in the DP during mid-to-late anagen is consistent with this hypothesis