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The prevalence of its reduced form in cells is due to the activity of glutathione reductase, which is both constitutive and inducible in response to oxidative stress

J Heart Lung Transplant 26(11):11771181 Sam F et al (2005) Increased reactive oxygen species production and functional alterations in antioxidant enzymes in human failing myocardium

The administration of ferrostatin-1 in an animal model has been found to alleviate the pathological phenotypes of trinitrobenzene sulfonic acid (TNBS)-induced CD-like colitis (17), providing ferroptosis as a potential therapeutic strategy in treating CD
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Epigenetic Mechanisms of Peptidergic Regulation of Gene Expression during aging of Human Cells