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The outermost layer is the competitive landscape of patents in the same therapeutic area held by other manufacturers, which identifies the white space for next-generation product development and alternative mechanisms of action

Adv Surg 33 : 261274 Mulligan K et al

[DOI] [PMC free article] [PubMed] [Google Scholar] 37.Shang Y, Zhi D, Feng G, Wang Z, Mao D, Guo S, et al

Treatment consists of intramuscular injections of cyanocobalamin, hydroxocobalamin, or mecobalamin at a dose of 1,000 g daily for one week, followed by weekly injections for one month, and then monthly maintenance therapy [3]

doi: 10.1016/S0140-6736(19)30427-1 4 ReijmerYDLeemansABrundelMKappelleLJBiesselsGJUtrecht Vascular Cognitive Impairment Study Group

Genetic Prediction of Sleep in Young Adults: Validity of Direct-to-Consumer Tests and Circadian Clock-Gene Variants Against 14-Day Sleep Diaries As direct-to-consumer (DTC) genetic testing becomes increasingly popular, many people receive reports predicting insomnia risk, chronotype, sleep habits, and other sleep-related traits