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However, surprisingly, an investigation of Ccs deficiency showed that while motor neurons in Ccs / mice showed significantly diminished incorporation of copper into wild-type and mutant Sod1, the absence of Ccs did not affect the onset and progression of motor neuron disease in fALS-linked SOD1-mutant mice

To confirm the specificity of this effect, shRNA targeting of GGT also decreased glutamate levels (Fig

[DOI] [PMC free article] [PubMed] [Google Scholar] 184.Simmering JE, Welsh MJ, Liu L, Narayanan NS, Pottegrd A

etoricoxib+erastin+DMSO: 1.05 0.08 nmol/mg protein vs